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Image Search Results
Journal: ASN NEURO
Article Title: Astrocyte Glutamate Uptake and Water Homeostasis Are Dysregulated in the Hippocampus of Multiple Sclerosis Patients With Seizures
doi: 10.1177/1759091420979604
Figure Lengend Snippet: Demyelinated lesion burden is similar in the HBSFRC cohort. A: Representative 5X stitched micrographs showing MOG immunoreactivity in MS & MS+S hippocampus visualized by HRP-DAB chromogen immunohistochemistry with hematoxylin counterstain. CA1, CA3, DG, & Sub are indicated. Demyelinated lesions are traced by red dashed line. Black dashed lines represent divisions between subregions. B–D: Quantification of lesion distribution in MS & MS+S tissues. Comparison of demyelinated lesion density in CA1 (B), CA3 (C), and DG (D) revealed no significant difference in lesion burden between MS & MS+S specimens. Unpaired t-test.
Article Snippet: For chromogen myelin labeling, after incubation with
Techniques: Tandem Mass Spectroscopy, Immunohistochemistry